This research was conducted to design an e-book based on Flippdf Professional in Arabic listening comprehension for Matriculation Programme. The Matriculation Programme is an Arabic preparation class that is prepared for prospective new students. This program aims to equalize Arabic competencies so that the students can communicate actively with Arabic in academic activities. However, this program still faces difficulties in attaining teaching materials, especially listening comprehension materials which make it difficult for educators to choose themes that are in accordance with student competencies, thus making the learning process ineffective. The development of an e-book based on the Flippdf Professional was chosen because of its advantages over printed books that can fulfil the needs and learning objectives of listening comprehension. The research design used in this research is Research and Development (R&D) comprised of five stages of the ADDIE model (Analyze, Design, Develop, Implementation, and Evaluation). The percentage value of validity from the material aspect was 86%, while the media aspect was 95%, and 91% from ehtlanguage aspect. Calculation results of trials conducted to determine the effectiveness of the product show that the ttest = - 16.42 and t table = 2,045 with the percentage of error tolerance of α=0,05% it can be concluded that ttable> tcount, and the product developed is effective to increase the student grade. The calculation result of the trials to determine the product's effectiveness for both the Experiment classes was considered effective with sig. (2-tailed) <sig.0.05 = 0.000.