The emergence of Industry 4.0 has a significant impact for many organizations such as higher education particularly in managing their knowledge of the curriculum. Nowadays, the world has shifted to more advanced technology, and this must be fulfilled by increasing human resources capacity. Meanwhile, many universities are unaware of this transition to re-manage their curriculum of knowledge for better adjustment of core competencies as the stakeholders expected. This research aims to determine the voice of stakeholder from Agro-industrial Technology enterprises by implementing House of Quality Matrix as the main tools. Besides, attempt to identify the main issues of the latest industrial revolution and match graduates' abilities as the company needed. The methodology applied was investigating selected stakeholders by utilizing questionnaire to gather information comprises graduate abilities, graduate competencies and technical skills. To sum up, this article generating customer ne