Triannisah, Kholifah (2024) FORMULATION OF FACIAL WASH GEL METHANOL EXTRACT OF (Areca catechu Linn.) AND TEST OF INHIBITANCE AGAINST Staphylococcus aureus. S1 Undergraduate thesis, Universitas Darussalam Gontor.

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Abstract

Commercial facial wash preparations that are widely marketed usually contain chemical antibacterial ingredients that contain isopropyl alcohol, SLS, and parabens which have negative impacts on health such as causing bacterial resistance, making the skin dry, disrupting the hormonal system. So a new innovation is needed with the use of natural antibacterials. One of the natural antibacterials is areca nut (Areca catechu L.) which contains alkaloids, flavonoids and tannins as antibacterials. Facial wash formulations that utilize natural ingredients can be used as an alternative to acne treatment caused by Staphylococcus aureus bacteria, which has fewer side effects compared to the use of chemical-based antibacterials. This study aimed to evaluate the physical quality of the facial wash gel preparations containing areca nut seed extract and assess their inhibitory activity against Staphylococcus aureus. Four formulations were prepared with varying extract concentrations: 0% (F0), 2.5% (F1), 5% (F2), and 7.5% (F3). The physical quality of the preparation was evaluated using qualitative descriptive methods and compared against SNI Standards. The antibacterial activity of the formulations was assessed using one-way ANOVA with ith a significance level of 95%. The results demonstrated that the characteristic of facial wash gel extract methanol areca nut results were red, smell is typical areca nut, texture is thick, homogeneous, pH 6-6.5, viscosity 3067.9-3467.1 cPs, spreadability 5.1-5.6 cm, and foaming power 84.3-93.1%. Formula 3 with an extract concentration of 7.5% have compound with alkaloid, flavonoid, saponin, and tannin demonstrating the strongest inhibitory effect, with an average inhibition zone diameter of 10.4 mm.

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