Thesis Published

INNOVATION OF NANOSPRAY SHALLOT SKIN EXTRACT (Allium cepa L) WITH OPTIMIZATION OF VEGETABLE OIL DELIVERY SYSTEM AS SUNBURN PROTECTION

Tsany, Nola Fairuz
Abstract
Indonesia is a tropical country with more sunlight overflow, one of which is UV (Ultraviolet) rays, which, if overexposed, will cause side effects such as sunburn, tanning, erythema and premature ageing. Sunburn is a vesicle on the skin with a history of exposure to sunlight, especially RUV (Ultraviolet Radiation) and often occurs in children or adults. One of the metabolite compounds that can block UV rays is quercetin, found in the skin of shallots (Allium cepa L.), which is made into a nanospray preparation with the optimization of the vegetable oil delivery system. This research aims to evaluate sunscreen activity in the formulation of shallot skin extract nanospray preparations with optimization of the vegetable oil delivery system. The research method used is laboratory experiments with descriptive analysis, including organoleptic, homogeneity, and Particle Size Analyzer (PSA) and statistical analysis, including testing pH, viscosity and SPF values. Data was processed using the SPSS Oneway ANOVA statistical program and paired-samples T-Test. The comparison of the concentration of vegetable oils and extracts used in each formulation was 3%:0% (F0), 3%:1% (F1), 6%:1% (F2), and 9%:1% (F3). The shallot skin extract nanospray's physical evaluation showed that each organoleptic formula's average result was milky brown, had a pH of 5- 6.5, a viscosity of 1-100 cPas, and an SPF value of 15. Based on the research that has been carried out, formula 3 with a concentration of shallot skin extract of 1% and vegetable oil 9% is the best formulation, namely pH value 6, viscosity 35, SPF value >15, particle size 29.41 nm and PDI 0.6.
Publication Details
InstitutionUniversitas Darussalam Gontor
DepartmentFarmasi
KeywordsKeywords: Shallot Skin, nano spray, Vegetable Oil, SPF (Sun Protector Factor)
Item ID5097
Deposited16 Jan 2025 15:53
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