FOMO is a sense of anxiety that arises when an individual experiences left out of information, experiences, and social connections deemed important by others, influenced by social media. Another study shows that the quantity of social media users in Indonesia are expected increase to 265 million by 2025, from 196.7 million previously. This trend could impact the mental health of individuals, especially Gen Z. From the perspective of the Qur’an, this phenomenon aligns with verses that describe human tendencies toward worldly matters. Additionally, the Qur’an fundamentally serves as a guidebook for all aspects of human life. This study aims to examine the phenomenon of FOMO from the perspective of scholars' interpretations of the Qur'an through an analysis of relevant Qur'anic terms and stories, as well as to offer solutions derived from Qur'anic exegesis to address this issue. The method used is the thematic method of Abu Hayyan Al-Farmawi, along with content analysis to understand the interrelation between verses. This research adopts a qualitative approach with a descriptive-analytical method to systematically illustrate the phenomenon of FOMO in Qur'anic interpretation and to analyze the meanings of related verses in depth. This study is library Research and draws from tafsir books as well as relevant research. This study reveals that several stories in Qur'anic interpretation are relevant to the phenomenon of FOMO, such as the stories of Habil and Qabil as well as Prophet Yusuf. Various interpretations indicate that these stories contain themes of social jealousy and envy, which can lead to irrational decisions. The solutions offered in Qur'anic interpretation to overcome FOMO include the practice of dhikr, maintaining piety and reliance on Allah (tawakkul), fasting, prioritizing the Hereafter as the ultimate life goal, and cultivating contentment (qana'ah) to avoid social comparison. The researcher acknowledges that this study has several limitations, particularly in its primary focus on only a few Qur'anic stories, whereas other stories may also hold similar relevance. Therefore, it is hoped that future researchers can complement and refine these shortcomings.