The recently emerged Covid-19 pandemic is greatly impacting every corner of human society throughout the world including human health. This study aimed to provide important insights into the response of food safety system on the perspective of preventing Covid-19 pandemic effect. A survey was conducted in Indonesia and Bangladesh to collect information from food companies about food safety preparedness associated with Covid-19, priorities in the prevention of pandemic effect on food companies, and the effect of the pandemic on the food supply chain. Hygiene and the use of masks and gloves are the two most significant attributes to prevent and combat the pandemic situation in terms of food safety, effective distance maintenance between persons, and restrain or limit visits to the object are considered as attributes with less significance. The retail part of the food supply chain was figured out as mainly affected by the pandemic as opposed to food storage was identified as least affected. The development of attitude in the food sector that not to compromise food safety at any moment is the strength to combat the pandemic crisis to retain the food safety standard globally