Environmental pollution due to hazardous and toxic waste (B3) is a serious problem that negatively affects the ecosystem. Based on data from the Ministry of Environment and Forestry (2023), 38.37% of the 38.3 million tonnes of national waste per year has not been managed properly. To increase the awareness of the younger generation towards waste management, this research aims to develop 3D simulation game-based learning media using Unreal Engine 5 with the First Person Shooter (FPS) genre. This game is designed to increase the participation of Junior High School (SMP) students in interactive learning about the impact of hazardous waste on the environment, utilizing available computer laboratories. In addition, this game integrates Islamic values about environmental conservation from QS Al-A'raf: 56. The game development method uses Mechanic Dynamic Aesthetic (MDA) Framework and Waterfall Software Development Life Cycle (SDLC) model. This game was tested through several stages, namely usability testing, compatibility testing, learning material test, learning media test, and user test. The test results show that this game is effective as a learning medium, with an average user assessment of 78.20%. This game is considered interesting, interactive, and easy to understand by students, and is able to increase their awareness of the dangers of hazardous waste. The conclusion of this research is that the Unreal Engine 5-based 3D simulation game can be an effective learning medium to increase students' literacy and awareness of the impact of B3 waste on the environment. This game also provides a fun and interactive learning experience, so it can support technology-based educational approaches in the digital era. Thus, this game can continue to be developed to be better and relevant to future learning needs.