OISCA (Organization for Industrial, Spiritual and Cultural Advancement) is an international non-governmental organization founded in Japan in 1961. OISCA focuses on sustainable development by incorporating industrial, spiritual and cultural aspects. The organization works in various countries, especially in Asia, to support projects related to human resource development, environmental conservation, and improving the welfare of rural communities. This research aims to explain the efforts of Organization Industial, Spiritual, and Culture Advancement (OISCA) as a non-profit organization in improving Human Resources (HR) from assistance in the form of programs, aiming to improve the welfare of farmers to teach nature conservation and greening the world. This research uses descriptive qualitative methods, using literature studies and also with interviews and observations as data collection techniques with the object of research describing the efforts of the OISCA organization in improving the quality of human resources, and also using greening methods, and nature conservation. In this study, the author found that the importance of non-profit organizations or non-governmental organizations such as OISCA that have the aim of greening the world in maintaining the balance of nature with their programs. OISCA is also an organization that is committed to increasing the capacity of the community on agricultural knowledge or in nature conservation. OISCA's efforts have proven to help the world through its membership countries in training sustainable agriculture and nature conservation, and also gradually improve the welfare of farmers and increase the capacity of the community.